ARYL AND HETEROARYL FUSED LACTAMS

ARYL AND HETEROARYL FUSED LACTAMS

This invention relates to compounds of general formula (I) in which R1, R2, U, V, L, M, R5, m, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZEHNDER LUKE RAYMOND, WYTHES MARTIN JAMES, EDWARDS MARTIN PAUL, TATLOCK JOHN HOWARD, KUMPF ROBERT ARNOLD, KUNG PEI-PEI, SUTTON SCOTT CHANNING, MCAPLINE INDRAWAN JAMES, RUI EUGENE YUANJIN, NINKOVIC SACHA
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This invention relates to compounds of general formula (I) in which R1, R2, U, V, L, M, R5, m, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.