Novel Imidazolines as dual inhibitors of MDM2 and MDMX

Novel Imidazolines as dual inhibitors of MDM2 and MDMX

Disclosed are compounds of Formula I or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, R1, R2 and R3 are as described in this application, and methods of using the compounds in the treatment of cancer.

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Bibliographische Detailangaben
Hauptverfasser: VU BINH THANH, ZHAO CHUNLIN, CHU XIN-JIE, LOVEY ALLEN JOHN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Disclosed are compounds of Formula I or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, R1, R2 and R3 are as described in this application, and methods of using the compounds in the treatment of cancer.