COMBINATIONS COMPRISING A DIPEPTIDYLPEPTIDASE - IV INHIBITOR

The present invention is directed to a combination comprising a dipeptidylpeptidase-IV (DPP-IV) inhibitor in free or pharmaceutically acceptable form, and at least one further antidiabetic compound or the pharmaceutically acceptable salt of such a compound, and optionally at least one pharmaceutical...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BALKAN BORK, HOLMES DAVID GRENVILLE, HUGHES THOMAS EDWARD, VILLHAUER EDWIN BEMARD
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to a combination comprising a dipeptidylpeptidase-IV (DPP-IV) inhibitor in free or pharmaceutically acceptable form, and at least one further antidiabetic compound or the pharmaceutically acceptable salt of such a compound, and optionally at least one pharmaceutically acceptable carrier, for simultaneous, separate or sequential use in the prevention, delay of progression or treatment of conditions mediated by DPP-IV, such as impaired glucose tolerance, conditions of impaired fasting plasma glucose, metabolic acidosis, ketosis, arthritis, obesity and osteoporosis, and preferably diabetes, especially type 2 diabetes mellitus.