FUSED PYRIMIDINE-DIONE DERIVATIVES AS TRPA1 MODULATORS

FUSED PYRIMIDINE-DIONE DERIVATIVES AS TRPA1 MODULATORS

The invention described herein relates to novel fused pyrimidinediones derivatives of formula (I) which are TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by T...

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Bibliographische Detailangaben
Hauptverfasser: CHAUDHARI SACHIN SUNDARLAL, DESHMUKH VISHAL GOVINDRAO, KHAIRATKAR-JOSHI NEELIMA, KUMAR SUKEERTHI, CHIKHALE RAJENDRA PRAKASH, MUKHOPADHYAY INDRANIL, KADAM ASHOK BHAUSAHEB, THOMAS ABRAHAM, PATIL NISHA PARAG, DHONE SACHIN VASANTRAO
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention described herein relates to novel fused pyrimidinediones derivatives of formula (I) which are TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). This invention also provides processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.