USE OF LRIG1 AS A BIOMARKER FOR IDENTIFYING A SUBJECT FOR APPLICATION OF ANTI-C-MET ANTIBODIES

A method of identifying a cell sample or subject suitable for treatment with an anti-c-Met antibody or antigen-binding fragment thereof that specifically binds to an epitope within a SEMA domain of a c-Met protein by determining the presence of LRIG1 in a cell sample from the subject, as well as rel...

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Bibliographische Detailangaben
Hauptverfasser: KIM KYUNG AH, KIM BO GYOU, LEE JI MIN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A method of identifying a cell sample or subject suitable for treatment with an anti-c-Met antibody or antigen-binding fragment thereof that specifically binds to an epitope within a SEMA domain of a c-Met protein by determining the presence of LRIG1 in a cell sample from the subject, as well as related methods and compositions.