QUINAZOLINONE DERIVATIVES AS PARP INHIBITORS

The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, L, X, Y and Z have defined meanings.

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Bibliographische Detailangaben
Hauptverfasser:	WOUTERS WALTER BOUDEWIJN LEOPOLD, VAN DUN JACOBUS ALPHONSUS JOSEPHUS, KENNIS LUDO EDMOND JOSEPHINE, MERTENS JOSEPHUS CAROLUS, SOMERS MARIA VICTORINA FRANCISCA, GUILLEMONT JEROME EMILE JORGES
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, L, X, Y and Z have defined meanings.