MUCOADHESIVE PARTICULATE FORMULATION FOR INDUCING ANTIGEN-SPECIFIC IMMUNE TOLERANCE

The present disclosure relates to a mucoadhesive composition, adapted for preventing and/or treating a pathological reaction of the immune system of an individual, by inducing a specific tolerance towards at least one antigen involved in said pathological reaction, comprising chitosan particles load...

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Bibliographische Detailangaben
Hauptverfasser: VAN OVERTVELT LAURENCE, RAZAFINDRATSITA ALAIN, SAINT-LU NATHALIE, TOURDOT SOPHIE, MOINGEON PHILIPPE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure relates to a mucoadhesive composition, adapted for preventing and/or treating a pathological reaction of the immune system of an individual, by inducing a specific tolerance towards at least one antigen involved in said pathological reaction, comprising chitosan particles loaded with said at least one antigen involved in the pathological reaction, wherein the size of the loaded chitosan particles is of more than 800 nm.