UNITARY PHARMACEUTICAL DOSAGE FORM

In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenofovir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein componen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HUSSAIN MUNIR A, DAHL TERRENCE C, LIPPER ROBERT A, JERZEWSKI ROBERT L, YANG TAIYIN, OLIYAI REZA, MENNING MARK M
Format: Patent
Sprache:eng
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Zusammenfassung:In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenofovir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein components 1 and 2 are in a stabilizing configuration. In preferred embodiments component 1 is made by dry granulation.