INHIBITORS OF LEUKOTRIENE PRODUCTION

The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein A1, A2, L1 and B are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorders. The present invent...

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Bibliographische Detailangaben
Hauptverfasser:	MARSHALL DANIEL RICHARD, ZINDELL RENEE M, TAKAHASHI HIDENORI, ZHANG QIANG, SNOW ROGER JOHN, YOUNG ERICK RICHARD ROUSH, RAZAVI HOSSEIN, SMITH KEENAN LANA LOUISE, BURKE MICHAEL JASON, SIBLEY ROBERT, KIRRANE, JR. THOMAS MARTIN, SORCEK RONALD JOHN, TAYLOR STEVEN JOHN, MAN CHUK CHUI, ZHANG YUNLONG, ABEYWARDANE ASITHA, BRUNETTE STEVEN RICHARD, TURNER MICHAEL ROBERT, PADYANA ANIL KUMAR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein A1, A2, L1 and B are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorders. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.