MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transport...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHOU JINGLAN, HAZELWOOD ANNA, MCCARTNEY JASON, GROOTENHUIS PETER, SINGH ASHVANI, HADIDA-RUAH SARA, VAN GOOR FRED
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.