PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING INFLAMATORY DISEASE OR ASTHMA CONTAINING AN EXTRACT OF DECASPERMUM FRUTICOSUM

The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma comprising the extract of Decaspermum fruticosum as an active ingredient. The extract of Decaspermum fruticosum of the present invention inhibited the increase of eosinoph...

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Bibliographische Detailangaben
Hauptverfasser:	LEE HYEONG KYU, AHN KYUNG SEOP, SON HWA-YOUNG, LEE KYOUNG-YOUL, LI WAN YI, KWON OK-KYOUNG, LEE JOONGKU, JOUNG HYOUK, JIN HANG, OH SEI RYANG, LEE MEE-YOUNG, LEE SANG WOO
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma comprising the extract of Decaspermum fruticosum as an active ingredient. The extract of Decaspermum fruticosum of the present invention inhibited the increase of eosinophils in bronchoalveolar lavage fluid of the ovalbumin-induced asthma animal model, had the activity of inhibiting the secretions of immunoglobulin and chemokine (Eotaxin) in bronchoalveolar lavage fluid and blood, and inhibited the secretions of NO and TNF-alpha in macrophages. Therefore, the extract of Decaspermum fruticosum of the present invention can be effectively used as an active ingredient of a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma, and of a health functional food for the prevention and improvement of inflammatory disease or asthma.