Novel Heterocyclic Compounds and Uses Thereof

New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase m...

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Hauptverfasser: ZHANG QIONG, POON DANIEL, HUANG ZILIN, RENHOWE PAUL A, SMITH AARON, MACHAJEWSKI TIMOTHY, MCKENNA MAUREEN, SENDZIK MARTIN, ANTONIOS-MCCREA WILLIAM R, JIN JEFF, XU YONGJIN, SHAFER CYNTHIA, CHEN ZHENG
Format: Patent
Sprache:eng
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Zusammenfassung:New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.