GLP-1 RECEPTOR AGONIST COMPOUNDS HAVING STABILIZED REGIONS

The disclosure provides GLP-1 receptor agonist compounds having stabilized regions corresponding to alpha-helical regions of the natural peptide compounds. The disclosure also provides benzamide-containing exendin-4 analogs and alkene-constrained exendin-4 analogs, both of which have stabilized regi...

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Hauptverfasser:	SOARES CHRISTOPHER J, GHOSH SOUMITRA S, COATS EUGENE, SHARMA ABHINANDINI, ALFARO-LOPEZ JOSUE
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
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creator	SOARES CHRISTOPHER J GHOSH SOUMITRA S COATS EUGENE SHARMA ABHINANDINI ALFARO-LOPEZ JOSUE
description	The disclosure provides GLP-1 receptor agonist compounds having stabilized regions corresponding to alpha-helical regions of the natural peptide compounds. The disclosure also provides benzamide-containing exendin-4 analogs and alkene-constrained exendin-4 analogs, both of which have stabilized regions corresponding to alpha-helical regions of exendin-4.
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title	GLP-1 RECEPTOR AGONIST COMPOUNDS HAVING STABILIZED REGIONS
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