METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES

Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents...

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Hauptverfasser: VAN ORDEN KAREN, MCKINNON KATHERINE, DOMON BRUNO, LEE CANDY, HE TAO, MESRI MEHDI, BIRSE CHARLES, JOSELOFF ELIZABETH, MOORE PAUL, RUBEN STEVE
Format: Patent
Sprache:eng
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Zusammenfassung:Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.