2-AMINOPYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR

2-AMINOPYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR

2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases,...

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Hauptverfasser: SAVALL BRAD M, FITZGERALD ANNIE E, SMITH DEBORAH M, RIZZOLIO MICHELE C, WEI JIANMEI, WIENER DANIELLE K, EDWARDS JAMES P, CAI HUI, VENABLE JENNIFER D, MANI NEELAKANDHA S, CHAVEZ FRANK, LIU JING, WOLIN RONALD L
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.