INDOLE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE

Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions...

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Bibliographische Detailangaben
Hauptverfasser: TAI VINCENT W.F, LEE CHANG-SUN, VERNER ERIK, BUGGY JOSEPH J, BALASUBRAMANIAN SRIRAM
Format: Patent
Sprache:eng
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Zusammenfassung:Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of HDAC8 activity.