PET IMAGING

A method for determining whether to administer a therapeutically effective amount of a receptor tyrosine kinase-inhibiting drug for tumor treatment, by determining a glucose uptake response in the tumor of a mammal. 18FDG-PET (2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography imaging) is...

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Bibliographische Detailangaben
Hauptverfasser:	MCKINLEY ELIOT T, BUGAJ JOSEPH E, MANNING HENRY C, WILD ROBERT C
Format:	Patent
Sprache:	eng
Schlagworte:	DIAGNOSIS HUMAN NECESSITIES HYGIENE IDENTIFICATION MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SURGERY
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Beschreibung
Zusammenfassung:	A method for determining whether to administer a therapeutically effective amount of a receptor tyrosine kinase-inhibiting drug for tumor treatment, by determining a glucose uptake response in the tumor of a mammal. 18FDG-PET (2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography imaging) is used as a predictive, non-invasive, pharmacodynamic biomarker of response following administration of drug.