Patient-Specific Modeling and Forecasting of Disease Progression

A computer-implemented method models and forecasts progression of a disease for a patient. The method includes, customizing a multivariate state space model for the patient based on test history data for the patient, the multivariate state space model comprising a model state representative of the d...

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Bibliographische Detailangaben
Hauptverfasser: LAVIERI MARIEL, HELM JONATHAN, VAN OYEN MARK, STEIN JOSHUA, MUSCH DAVID, SHELL GREGG
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A computer-implemented method models and forecasts progression of a disease for a patient. The method includes, customizing a multivariate state space model for the patient based on test history data for the patient, the multivariate state space model comprising a model state representative of the disease progression for the patient, generating, using the customized multivariate state space model, a forecast of the model state based on a current representation of the model state and current measurement data for a test that observes measurements relevant to the progression of the disease, and converting the model state forecast into a disease progression probability.