Optimized Fc Variants and Methods for their Generation

The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

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Bibliographische Detailangaben
Hauptverfasser: CHIRINO ARTHUR J, DESJARLAIS JOHN R, KARKI SHER BAHADUR, LAZAR GREGORY ALAN, DANG WEI, DOBERSTEIN STEPHEN KOHL, HAYES ROBERT J, VAFA OMID
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.