NOVEL TYROSINE KINASE INHIBITORS

Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.

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Bibliographische Detailangaben
Hauptverfasser: MIKEL CHARLES CHAMCHOUMIS, CHUCHOLOWSKI ALEXANDER, THIRUVAZHI MOHAN SANTHANAM, KADUSHKIN ALEKSANDER, ZHU TONG, MCGRATH DOUGLAS ERIC, GREGOR VLAD EDWARD, ZOZULYA SERGEY, LIU YAHUA, ANIKIN ALEXEY VYACHESLAVOVICH, YAN ZHENG, JIANG LUYONG, KHASANOV ALISHER, VAIRAGOUNDAR RAJENDRAN, VAVILALA GOVERDHAN REDDY, PICKENS JASON CONRAD
Format: Patent
Sprache:eng
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Zusammenfassung:Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.