HARD CAPSULE AND METHOD FOR PRODUCING SAME

This invention provides a hard capsule that has excellent stability even when filled with a solvent for dissolving poorly soluble drugs, and that also achieves reduction in disintegration time, thereby ensuring excellent solubility. Specifically, the hard capsule of the present invention has a film...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MORIUCHI TOSHIAKI, HAYASHI YUSUKE, YOSHINO HIROYUKI, KOJO AKANE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention provides a hard capsule that has excellent stability even when filled with a solvent for dissolving poorly soluble drugs, and that also achieves reduction in disintegration time, thereby ensuring excellent solubility. Specifically, the hard capsule of the present invention has a film comprising: (A) a polymer or copolymer obtained by polymerizing or copolymerizing, in the presence of polyvinyl alcohol and/or a derivative thereof, at least one polymerizable vinyl monomer represented by Formula (1): H2C C(R1)-COOR2   (1) wherein R1 represents hydrogen or methyl, and R2 represents hydrogen or alkyl having 1 to 4 carbon atoms; and (B) native gellan gum.