METHODS OF MODULATING FUCOSYLATION OF GLYCOPROTEINS

The present invention provides methods and materials useful for monitoring and regulating the glycosylation of glycoproteins that are recombinantly produced from cells. In particular, methods are provided for monitoring and regulating levels of cellular indicators which affect the level of fucosylat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: COLLINS BRIAN E, MILLEA KEVIN, BULIK DOROTA A, THIRUNEELAKANTAPILLAI LAKSHMANAN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides methods and materials useful for monitoring and regulating the glycosylation of glycoproteins that are recombinantly produced from cells. In particular, methods are provided for monitoring and regulating levels of cellular indicators which affect the level of fucosylation produced by cells.