Novel Ethanediamone Hepcidine Antagonists

The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for treatment of disorders in iron metabolism, such as, in particular, iron deficiency diseases and anaemias, in particular anaemi...

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Bibliographische Detailangaben
Hauptverfasser: YAU WEI TSUNG, COURTNEY STEPHEN M, DUERRENBERGER FRANZ, RIDGILL MARK P, JAEGER STEFAN, YARNOLD CHRISTOPHER J, BUHR WILM, CORDEN VINCENT A, BURCKHARDT SUSANNA, DAVENPORT TARA, GEISSER PETER O, FUNK FELIX, SLACK MARK
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for treatment of disorders in iron metabolism, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and AI: anaemia of inflammation).