HUMANISED PSORIASIS MODEL

The present invention relates to a new humanised animal model of psoriasis. Said model is generated by grafting humanised skin equivalents in the animal, injecting T lymphocytes and cytokines involved in the generation of the disease in humans, and performing the tape-stripping technique in order to...

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Bibliographische Detailangaben
Hauptverfasser:	NECHAEVSKY MARCELA DEL RIO, JORCANO NOVAL JOSE L, GARCIA DIEZ MARTA, GUERRERO ASPIZUA SARA, LAGUZZI FERNANDO LARCHER, CARRETERO TRILLO MARTA, INFIESTA ALVARO MEANA
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY CARE OF BIRDS, FISHES, INSECTS FISHING FORESTRY HUMAN NECESSITIES HUNTING INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING NEW BREEDS OF ANIMALS PHYSICS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR TESTING TRAPPING
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Beschreibung
Zusammenfassung:	The present invention relates to a new humanised animal model of psoriasis. Said model is generated by grafting humanised skin equivalents in the animal, injecting T lymphocytes and cytokines involved in the generation of the disease in humans, and performing the tape-stripping technique in order to generate damage in said grafted equivalents. Said model may be used to study the disease, as well as for the identification and evaluation of the efficacy of compounds against said disease.