PHARMACEUTICAL COMPOSITION

The invention concerns a co-processed additive for a solid-dose pharmaceutical composition, the additive comprising from about 50% to 99.5% by weight of at least one pharmaceutical compression aid and from about 0.5% to 50% by weight of at least one pharmaceutical lubricant, the melting point of sai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MAEGLI JACK, CROWLEY MICHAEL, GAGE AMANDA, O'REILLY TIMOTHY
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention concerns a co-processed additive for a solid-dose pharmaceutical composition, the additive comprising from about 50% to 99.5% by weight of at least one pharmaceutical compression aid and from about 0.5% to 50% by weight of at least one pharmaceutical lubricant, the melting point of said compression aid(s) being higher than the melting point of said lubricant(s). The co-processed additive may be in the form of a physically bound composite whereby the lubricant is associated with the surface of the compression aid particles.