Devices and Methods for Tissue Engineering

A tissue engineering scaffold of interconnected and bonded fiber having a property with a value that is spatially distributed in at least two regions is provided. The scaffold has at least two regions with properties, such as porosity, strength, elastic modulus, osteoconductivity, and bioactivity th...

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Bibliographische Detailangaben
Hauptverfasser:	LIU JAMES JENQ, KREVOLIN JANET L
Format:	Patent
Sprache:	eng
Schlagworte:	AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DIAGNOSIS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE IDENTIFICATION MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PERFORMING OPERATIONS PROSTHESES SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDEDFOR SHAPING OR JOINING OF PLASTICS SURGERY TRANSPORTING TREATMENT OR PROTECTION OF EYES OR EARS WORKING OF PLASTICS WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL
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Beschreibung
Zusammenfassung:	A tissue engineering scaffold of interconnected and bonded fiber having a property with a value that is spatially distributed in at least two regions is provided. The scaffold has at least two regions with properties, such as porosity, strength, elastic modulus, osteoconductivity, and bioactivity that can be controlled and modified through fabrication processes that alter the pore size, pore size distribution, composition, and bonding of fiber and other additives. The value of the property can be provided with a gradient between each of the adjacent spatially distributed regions.