TARGETING NUCLEIC ACIDS IN MITOCHONDRIA

The present invention relates to a shuttle system with which nucleic acids of interest may be imported into a mitochondrion. This system is based on the use of a fusion protein between a mitochondrial targeting sequence and a protein binding a nucleic acid of interest. This shuttle system is for exa...

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Bibliographische Detailangaben
Hauptverfasser:	SIEBER FRANCOIS, DROUARD LAURENCE, PLACIDO ANTONIO
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW PLANTS OR PROCESSES FOR OBTAINING THEM ORGANIC CHEMISTRY PEPTIDES PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a shuttle system with which nucleic acids of interest may be imported into a mitochondrion. This system is based on the use of a fusion protein between a mitochondrial targeting sequence and a protein binding a nucleic acid of interest. This shuttle system is for example useful in agronomics, in the field of gene therapy, and within the scope of research products aiming at characterizing the function of mitochondrial genes.