CELLULAR ASSAY EMPLOYING DETECTABLE PROTEIN

Provided herein are assays useful, for example, for determining the activity of a protein involved in a cellular process. In some embodiments, the activity of the protein is assessed using a nucleic acid tag, and in particular, by detecting the presence of a nucleic acid tag. Such assays can be used...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WODICKA LISA M, TREIBER DANIEL KELLY, LEWIS WARREN G
Format: Patent
Sprache:eng
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Zusammenfassung:Provided herein are assays useful, for example, for determining the activity of a protein involved in a cellular process. In some embodiments, the activity of the protein is assessed using a nucleic acid tag, and in particular, by detecting the presence of a nucleic acid tag. Such assays can be used, for example, to study the effects of test compounds as modulators, e.g., inhibitors, agonists and antagonists, of protein activity.