Heterologous Expression of Termite Cellulases Yeast

The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells w...

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Hauptverfasser: BREVNOVA ELENA E, WISWALL ERIN, MELLON MARK, MCBRIDE JOHN, WARNER ANNE, GANDHI CHHAYAL, RAJGARHIA VINEET
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.