PURGING OF AN EX VIVO HEMATOPOIETIC STEM CELL CULTURE OF CANCER CELLS

A use of a composition comprising an SDF-1 peptide having the sequence KGVSLSYR is taught. The composition can be used to purge an ex vivo hematopoietic stem cell culture of cancer cells for engraftment in a mammal by administering the composition to the ex vivo hematopoietic stem cell culture in an...

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Hauptverfasser: CASHMAN JOANNE, MERZOUK AHMED, ARAB LAKHDAR, SAXENA GEETA, EAVES CONNIE J, RICHTER MARY A, TUDAN CHRISTOPHER R, CLARK-LEWIS IAN, CLARK-LEWIS MICHAEL, SALARI HASSAN
Format: Patent
Sprache:eng
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Zusammenfassung:A use of a composition comprising an SDF-1 peptide having the sequence KGVSLSYR is taught. The composition can be used to purge an ex vivo hematopoietic stem cell culture of cancer cells for engraftment in a mammal by administering the composition to the ex vivo hematopoietic stem cell culture in an effective amount.