Ronin is Essential for Perpetuity of Mouse ES Cells, and Acts Independently of Canonical Pathways

The present invention, therefore, encompasses compositions and methods comprising Ronin, a Ronin activator, and methods of their use for maintaining the perpetuity of an ES cell phenotype.

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Bibliographische Detailangaben
Hauptverfasser: DEJOSEZ MARION, ZITUR LAURA JO, KRUMENACKER JOSHUA, ZWAKA THOMAS P
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention, therefore, encompasses compositions and methods comprising Ronin, a Ronin activator, and methods of their use for maintaining the perpetuity of an ES cell phenotype.