CXCR2 INHIBITORS

CXCR2 INHIBITORS

The invention relates to compounds of the formula I: in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LI HUI, SHER ROSY, SHIMSHOCK STEPHEN J, DEDIO JUERGEN, HEITSCH HOLGER, HACHTEL STEPHANIE, GRUENEBERG SVEN, LANTER CAROLINA L, WEICHSEL ALEKSANDRA, CZECHTIZKY WERNGARD, KOSLEY, JR. RAYMOND W
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention relates to compounds of the formula I: in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.