MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS

The present invention provides methods for the use of compounds having formula (I) in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1-R11, t, X, Y, Z, and n are as defined herein.

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Bibliographische Detailangaben
Hauptverfasser:	FUJITA MASANORI, WANG JOHN (YUAN), KAWAI TAKATOSHI, GOTO MASAKI, LEMELIN CHARLES-ANDRE, MIZUI YOSHIHARU, LI XIANG-YI, SHIROTA HIROSHI, EGUCHI YOSHIHITO, HARMANGE JEANRISTOPHE, GUSOVSKY FABIAN, YONEDA NAOKI, MURAMOTO KENZO, CHIBA KENICHI, DU HONG, KAWAKAMI YOSHIYUKI, BOIVIN ROCH, TANAKA ISAO, KUBOI YOSHIKAZU, YAMAMOTO SATOSHI, KOTAKE MAKOTO, JIANG YIMIN, CHOW JESSE, KIMURA AKIFUMI, SPYVEE MARK, INOUE ATSUSHI, SHEN YONGUN, SAKURAI HIDEKI, MATSUSHIMA TOMOHIRO, KAWADA MEGUMI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides methods for the use of compounds having formula (I) in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1-R11, t, X, Y, Z, and n are as defined herein.