Stable Topical Formulation Comprising Voriconazole

The present invention relates to a stable topical formulation comprising an effective amount of voriconazole or its pharmaceutically acceptable salt, and at least a pharmaceutical carrier; a process for preparing the same and use of such formulation for the treatment of local or non-systemic fungal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KHACHANE VASANT SITARAM, BASA SHRADHANJALI, BHAMRE NITIN BABUBAL, KOTWAL RUPESH SUBHASHCHANDRA, SOMNATHE NITIN DASHRATHRAO, DHUPPAD ULHAS RAMESHCHANDRA, SATPUTE RAVINDRA MORESHWAR, MAHAJAN NARAYAN TUKARAM
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a stable topical formulation comprising an effective amount of voriconazole or its pharmaceutically acceptable salt, and at least a pharmaceutical carrier; a process for preparing the same and use of such formulation for the treatment of local or non-systemic fungal infections in a subject. In particular, the present invention relates to a stable topical formulation exhibiting a storage stability at a temperature of about 40° C. and a relative humidity of about 75% for a period of at least 3 months, and contains not more than 9% w/w total impurities (based on total weight of the formulation) formed upon storage.