PROTEIN MODULATORS

The present invention relates to modulators of the Neuregulin (NRG) family, particularly NRG1 and more particularly NRG1 , and most particularly NRG1 1. The present invention also relates to the use of such modulators to inhibit goblet cell hyperplasia and therefore also relates to the use of such m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	JACKSON ALAN, JONES CAROL ELIZABETH
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	The present invention relates to modulators of the Neuregulin (NRG) family, particularly NRG1 and more particularly NRG1 , and most particularly NRG1 1. The present invention also relates to the use of such modulators to inhibit goblet cell hyperplasia and therefore also relates to the use of such modulators in the treatment or prevention of human diseases and disorders featuring pathological mucus production such as COPD, CF, chronic bronchitis and asthma.