Adenoviruses Mutated In The VA Genes For Cancer Treatment

This invention refers to the use of an adenovirus for cancer treatment, being this adenovirus defective in its virus-associated (VA) RNAs. Said adenovirus has a mutation in the VAI or VAII gene sequence or both. This adenovirus may also have mutations in the sequences controlling expression of the V...

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Hauptverfasser: CASCALLO PIQUERAS MANEL MARIA, BONASTRE RAMON ALEMANY
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention refers to the use of an adenovirus for cancer treatment, being this adenovirus defective in its virus-associated (VA) RNAs. Said adenovirus has a mutation in the VAI or VAII gene sequence or both. This adenovirus may also have mutations in the sequences controlling expression of the VA RNAs.