DEXLANSOPRAZOLE PROCESS AND POLYMORPHS

Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methy...

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Hauptverfasser:	SIGALA ASHOK, BADDAM SUDHAKAR REDDY, GANGULA SRINIVAS, NAREDLA ANITHA, NEELAM UDAYKUMAR, PEDDIREDDY SUBBAREDDY, MUDUNURU SATISH VARMA, TUMMALA ARJUNKUMAR, MANNE NAGARAJU, TUMMIDI MADHU KIRAN, KOLLA NAVEEN KUMAR, PATIL SUMEET VISHWASRAO, SHINDE SACHIN GULABRAO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and 2-[(R)-[(4-nitro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, and methods for their preparation.