NOVEL HETEROCYCLES

Described are novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. These compounds are useful in the trea...

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Hauptverfasser:	KACHHADIA VIRENDRA, JANARTHANAM VENKATESAN, GADDAM OM, GADDE SATHYANARAYANA, VISHWAKARMA LOLAKNATH SANTOSH, RAMACHANDRAN UMA, NARAYANAN SHRIDHAR, NARAYANAM MARUTHIKUMAR, BALASUBRAMANIAN GOPALAN, BHAKIARAJ DURAIRAJ PETER, NARASIMHAN KILAMBI, NARAYANAN SUKUNATH, PARAMESWARAN VENKATESAN, THARA SATHYA NARAYANA, RAJAGOPAL SRIRAM, GADDAM NISHIKANTH REDDY, SAXENA SANJEEV, SHARMA GANAPAVARAPU VEERA RAGHAVA, SAPPANIMUTHU THIRUNAVUKKARASU, SURENDRAN NARAYANAN, TADIPARTHI RAVIKUMAR, SRINIVAS VISWESWARA AKELLA SATYA SURYA
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Described are novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. These compounds are useful in the treatment of immunological diseases, inflammation, pain disorder, rheumatoid arthritis; osteoporosis; multiple myeloma; uveititis; acute and chronic myelogenous leukemia; atherosclerosis; cancer; cachexia; ischemic-induced cell damage; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; ARDS; psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact dermatitis; muscle degeneration; asthma; COPD; bone resorption diseases; multiple sclerosis; sepsis; septic shock; toxic shock syndrome and fever. More particularly these compounds are useful as PDE4 inhibitors and are useful for treating PDE4 mediated diseases.