Method of enhancing ocular penetration of a drug in an eyedrop

A method of enhancing ocular penetration of a drug in an eyedrop by administering to an eye, an eyedrop containing, particulate agar having a weight-average molecular weight of from 5,000 to 1,200,000, the particulate agar being obtained by dissolving agar into an aqueous solution by heating and the...

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Hauptverfasser: ARAKI MIHO, INOHARA MASAHIRO, UE MASAKI, YOSHIKAWA MASAHITO, YOKOTA MITSURU, TANIGUCHI TAKASHI, SHIMOYAMA NAOKI
Format: Patent
Sprache:eng
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Zusammenfassung:A method of enhancing ocular penetration of a drug in an eyedrop by administering to an eye, an eyedrop containing, particulate agar having a weight-average molecular weight of from 5,000 to 1,200,000, the particulate agar being obtained by dissolving agar into an aqueous solution by heating and then cooling the resultant mixture to avoid gelling, while applying a stress by vibration, shearing, stirring, compression or pulverizing, wherein the particulate agar is in an amount of 0.1 to 10 wt %.