PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS OR OBESITY COMPRISING PHENYLTETRAZOLE DERIVATIVE

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS OR OBESITY COMPRISING PHENYLTETRAZOLE DERIVATIVE

A phamaceutical composition comprising a phenyltetrazole derivative of formula (I) or a pharmaceutical acceptable salt thereof is effective in preventing or treating osteoporosis, obesity, diabetes, or hyperlipidemia, by regulating protein TAZ. wherein, A is ethyl or n-butyl; R1 is methyl, -CH2OH, -...

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Bibliographische Detailangaben
Hauptverfasser: KIM NAK JEONG, HEO JUNG NYOUNG, HWANG EUN SOOK, KANG NAMSOOK, SUH JEE HEE, YI KYU YANG, HONG JEONG-HO, YOO SUNG-EUN, BAE MYUNG-AE, CHANG SUNG YOUN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:A phamaceutical composition comprising a phenyltetrazole derivative of formula (I) or a pharmaceutical acceptable salt thereof is effective in preventing or treating osteoporosis, obesity, diabetes, or hyperlipidemia, by regulating protein TAZ. wherein, A is ethyl or n-butyl; R1 is methyl, -CH2OH, -CO2CH3, -CH2F, -CH(OCH3)2, -CH2OC( O)CH3, styryl or -CH2OCH2SCH3; R2 is H, Br, -CO2CH3, phenyl, pyridin-2-yl, pyridin-3-yl,  or styryl; R3 is H or methyl; X is CH or N; and P is H or -CH(CH3)OCH2CH3.