METHOD AND ARRANGEMENT FOR FORMING VARIABLE COLOR PHARMACEUTICAL PRODUCTS

Methods and arrangements for forming a color gradient on a pharmaceutical dosage forms such as tablets are disclosed. In preferred aspects of the invention, a coating layer is applied to a tablet core so that the coating layer is different from the color of the tablet core. The coating layer is etch...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	DOLBIER MARC, YODER STEVEN L, KETTINGER FREDERICK R
Format:	Patent
Sprache:	eng
Schlagworte:	AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING CHEMICAL SURFACE TREATMENT CHEMISTRY COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATIONOR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY IONIMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL COATING MATERIAL WITH METALLIC MATERIAL COATING METALLIC MATERIAL COMPOSITIONS BASED THEREON DIFFUSION TREATMENT OF METALLIC MATERIAL GENERAL PROCESSES OF COMPOUNDING HUMAN NECESSITIES HYGIENE INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION INGENERAL MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PERFORMING OPERATIONS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDEDFOR SHAPING OR JOINING OF PLASTICS SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THESURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION THEIR PREPARATION OR CHEMICAL WORKING-UP TRANSPORTING WORKING OF PLASTICS WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL WORKING-UP
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Beschreibung
Zusammenfassung:	Methods and arrangements for forming a color gradient on a pharmaceutical dosage forms such as tablets are disclosed. In preferred aspects of the invention, a coating layer is applied to a tablet core so that the coating layer is different from the color of the tablet core. The coating layer is etched by one or more lasers to remove selected portions thereof and reveal the core. Removal of selected portions of the coating layer, while other portions remain unetched by the laser(s), causes a variation in the color of the coating layer. The color of the tablet core may be visible at locations at which portions of the coating layer have been entirely removed while the color of the coating layer, i.e., the color of any of the color coatings thereof, is visible at locations at which portions of the coating layer have been only partially removed or not removed at all.