NON-NUCLEOTIDE COMPOSITION FOR INHIBITING PLATELET AGGREGATION

This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising a...

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Bibliographische Detailangaben
Hauptverfasser:	TU CHI, ALFARO-LOPEZ LORENZO J, SHAVER SAMMY R, HARVEY DANIEL F, WATSON PAUL S, BOYER JOSE L, ABREO MELWYN A, FENG YANGBO, PLOURDE, JR. ROBERT, KHASONOVA TATYANA V, DOUGLASS, III JAMES G
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a non-nucleotide compound, preferably a P2Y12 receptor antagonist compound, wherein said amount is effective to inhibit platelet aggregation. The compounds useful for this invention include compounds of general Formulae I and III-XII, or salts, hydrates, and solvates thereof. The present invention also provides novel compounds of Formulae I and III-XII.