Streptococcus pneumoniae Antigens and Vaccines

The present invention relates to novel vaccines for the prevention or attenuation of infection by Streptococcus pneumoniae. The invention further relates to isolated nucleic acid molecules encoding antigenic polypeptides of Streptococcus pneumoniae. Antigenic polypeptides are also provided, as are v...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FANNON MICHAEL R, ROSEN CRAIG A, KUNSCH CHARLES A, DOUGHERTY BRIAN, CHOI GIL H, BARASH STEVEN C, DILLON PATRICK J
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to novel vaccines for the prevention or attenuation of infection by Streptococcus pneumoniae. The invention further relates to isolated nucleic acid molecules encoding antigenic polypeptides of Streptococcus pneumoniae. Antigenic polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention additionally relates to diagnostic methods for detecting Streptococcus nucleic acids, polypeptides and antibodies in a biological sample.