NOVEL CHEMOTHERAPEUTIC AGENTS AGAINST INFLAMMATION AND CANCER

Novel compounds, their methods of preparation and use in therapies related to cancer and inflammation are provided. Compounds comprise esters of cinnamic acid, vanillic acid and 4-hydroxy cinnamic acid and derivatives and salts thereof. Compounds with novel benzofuran lignan structure as a potent an...

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Bibliographische Detailangaben
Hauptverfasser: BOSE JULIE SAHA, GANGAN VIJAY
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Novel compounds, their methods of preparation and use in therapies related to cancer and inflammation are provided. Compounds comprise esters of cinnamic acid, vanillic acid and 4-hydroxy cinnamic acid and derivatives and salts thereof. Compounds with novel benzofuran lignan structure as a potent antimitotic agent and inducer of apoptosis are provided. Formulations and methods for treatment of diseases mediated by NF-kappaB are also provided.