PROLINAMIDE DERIVATIVES AS MODULATORS OF VOLTAGE-GATED SODIUM CHANNELS

PROLINAMIDE DERIVATIVES AS MODULATORS OF VOLTAGE-GATED SODIUM CHANNELS

The invention relates to quaternary α-aminocarboxyamide derivatives of formula (I) and their pharmaceutically salts or solvates wherein R1 is H or CH3; and R2 is H or CH3, for treating diseases and conditions mediated by modulation of voltage-gated sodium channels.

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Bibliographische Detailangaben
Hauptverfasser: ALVARO GIUSEPPE, MARASCO AGOSTINO, BERGAUER MARKUS
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to quaternary α-aminocarboxyamide derivatives of formula (I) and their pharmaceutically salts or solvates wherein R1 is H or CH3; and R2 is H or CH3, for treating diseases and conditions mediated by modulation of voltage-gated sodium channels.