Renin Inhibitors

Described are compounds which bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protea...

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Bibliographische Detailangaben
Hauptverfasser:	CLAREMON DAVID, TICE COLIN, GHAVIMI-ALAGHA BAHMAN, TERRELL LAMONT R, DILLARD LAWRENCE W, SIMPSON ROBERT D, SEMUS SIMON, ISHEBENKO ALEXEY V, KALLANDER LARA S, ZHANG JING, MCGEEHAN GERARD, YUAN JING, CACATIAN SALVACION, XU ZHENRONG, SINGH SURESH B, KNAPP-REED BETH A, TRAN TRITIN, LU QING, GHIRLANDA DAMIAMO, ZHAO WEI, HOU XIAOPING, FLAHERTY PATRICK T, LAWHORN BRIAN, BALDWIN JOHN J
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Described are compounds which bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protease related disorders in a subject in need thereof.