COMPOUNDS CAPABLE OF ACTIVATING CHOLINERGIC RECEPTORS

COMPOUNDS CAPABLE OF ACTIVATING CHOLINERGIC RECEPTORS

The present invention generally relates to nicotinic compounds, in the form of aryl substituted olefinic compounds, as well as pro-drug, N-oxide, metabolite and pharmaceutically acceptable salt forms thereof. Methods of modulating neurotransmitter release via administration of the compounds, pro-dru...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LIPPIELLO PATRICK M, CROOKS PETER A, DULL GARY M, HADIMANI SRISHAILKUMAR B, BENCHERIF MEROUANE, CALDWELL WILLIAM S, WAGNER JARED M, BHATTI BALWINDER S, PARK HAEIL
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention generally relates to nicotinic compounds, in the form of aryl substituted olefinic compounds, as well as pro-drug, N-oxide, metabolite and pharmaceutically acceptable salt forms thereof. Methods of modulating neurotransmitter release via administration of the compounds, pro-drugs, N-oxides and/or pharmaceutically acceptable salts are also disclosed.