Radioactive material containing chitosan for inhibiting cancer and preparation method thereof

A radioactive material containing chitosan for inhibiting cancer and a preparation method thereof are revealed. The adioactive material containing chitosan is formed by using SOCTA chelating agent to connect chitosan and radionuclides such as 188Re, and Tc-99m etc. The preparation method of the radi...

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Hauptverfasser: LIANG TE-SHENG, LUO TSAI-YUEH, LIOU CHING-JUN, WU YU-LUNG, CHEN JIAN-WEN, HSU KWEI-LUEN, SHENG CHANG-MAU, LIN JIN-JENN, SHEU JYH-DAW, TANG IUNG
Format: Patent
Sprache:eng
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Zusammenfassung:A radioactive material containing chitosan for inhibiting cancer and a preparation method thereof are revealed. The adioactive material containing chitosan is formed by using SOCTA chelating agent to connect chitosan and radionuclides such as 188Re, and Tc-99m etc. The preparation method of the radioactive material containing chitosan includes the steps of: prepare SOCTA-Chitosan compound; and prepare M(radionuclide)-SOCTA-Chitosan compound. By biocompatibility and clotting in alkaline environment of human blood of chitosan, the radioactive material containing chitosan is injected into cancer and staying there for a long time so as to achieve effectively treatment.