NOVEL CURCUMIN DERIVATIVE

The present invention provides a novel compound that is structurally similar to curcumin and has a suppressive effect on A aggregation, a degradative effect on A aggregates, an inhibitory effect on -secretase, and a protective effect on neurons. The novel compound is a compound represented by the fo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	NIIDOME TETSUHIRO, SHIMMYO YOSHIARI, HIJIKURO ICHIRO, TAKAHASHI TAKASHI, SUGIMOTO HACHIRO, KIHARA TAKESHI
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention provides a novel compound that is structurally similar to curcumin and has a suppressive effect on A aggregation, a degradative effect on A aggregates, an inhibitory effect on -secretase, and a protective effect on neurons. The novel compound is a compound represented by the following general formula (Ia) or a salt thereof: wherein R1 represents a 4-hydroxy-3-methoxyphenyl group or the like, and R2 represents a 1H-indol-6-yl group or the like.