Novel tumor necrosis factor receptor homolog and nucleic acids encoding the same

The present invention is directed to novel polypeptides having homology to members of the tumor necrosis factor receptor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide mol...

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Hauptverfasser: GODDARD AUDREY, ASHKENAZI AVI J, GURNEY AUSTIN, MARSTERS SCOT A, PITTI ROBERT M, WOOD WILLIAM I
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention is directed to novel polypeptides having homology to members of the tumor necrosis factor receptor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.